Research activity:

• Topoisomerases as a molecular targets for new derivatives of anticancer drugs.
• Biological properties of the new anticancer prodrugs.
• The effect of the new anticancer drugs on the apoptosis and cell signaling in the breast cancer cells.

Laboratory techniques:

• spectroscopic techniques
  • spectrometry UV/VIS
  • spectrofluorimetry
• flow cytometry
• nanocalorimetry ITC and DSC
• electrophoretic techniques
  • electrophoresis with immunoblot

Publications:
 

• Pawłowska N., Czajkowska A., Bielawska A. Arthrospira platensis - "green gold" of cosmetology. Pol. J. Cosmet., 19 (3) s. 199-205 (2016)
• Czarnomysy R., Bielawski K., Muszyńska A., Bielawska A., Gornowicz A.: Biological evaluation of dimethylpyridine-platinum complexes with potent antiproliferative activity. J. Enzyme Inhib. Med. Chem., 16 (2016)
• Kierklo A., Pawińska M., Tokajuk G., Popławska B., Bielawska A., Bielawski K. Effect of dentine bondings in combination with peroxide bleaching agents on the biosynthesis of DNA in human gingival fibroblasts. J. Stomatol., 69 (2) s. 153-161 (2016)
• Bielawska A., Czajkowska A. Wykorzystanie winorośli właściwej (Vitis vinifera) w prewencji chorób nowotworowych. Aktualności Medyczne, 4 s. 46-49 (2016)
• Czajkowsa A., Pawłowska N., Bielawska A. Vitis vinifiera as a source of youthfulness - the applicatyion of grapevine (Vitis vinifera) in cosmetology. Pol. J. Cosmet., 19 (2) s. 98-103 (2016)
• Czarnomysy R., Bielawska A., Muszyńska A., Bielawski K.: Effects of novel alkyl pyridine platinum complexes on apoptosis in Ishikawa endometrial cancer cells. Med. Chem., 11 (6) s. 540-550 (2015)
• Bielawska A.  Lekarstwo z natury - czarnuszka siewna (Nigella sativa). Aktualności Medyczne. 1 s. 40-42 (2015)
• Mojzych M., Ceruso M., Bielawska A., Bielawski K., Fornal E., Supuran C. T.: New pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors. Bioorg. Med. Chem., 23 (13) s. 3674-3680 (2015)
• Plech T., Kaproń B., Paneth A., Wujec M., Czarnomysy R., Bielawska A., Bielawski K., Trotsko N., Kuśmierz E., Paneth P.: Search for human DNA topoisomerase II poisons in the group of 2,5-disubstituted-1,3,4-thiadiazoles. J. Enzyme Inhib. Med. Chem., 30 (6) s. 1021-1026 (2015)
• Karczmarzyk Z., Wysocki W., Urbańczyk-Lipkowska Z., Kalicki P., Bielawska A., Bielawski K., Ławecka J.: Synthetic approaches for sulfur derivatives containing 1,2,4-triazine moiety: their activity for in vitro screening towards two human cancer cell lines. Chem. Pharm. Bull., 63 (7) s. 531-537 (2015)
• Kostecka K.B., Popławska B., Bielawska A. Sztuczna skóra - nadzieja medycyny i kosmetologii. Pol. J. Cosmet. 18 s. 51-54 (2015)
• Gornowicz A., Bielawska A., Czarnomysy R., Gabryel-Porowska H., Muszyńska A., Bielawski K.: The combined treatment with novel platinum (II) complex and anti-MUC1 increases apoptotic response in MDA-MB-231 breast cancer cells. Mol. Cell. Biochem., 408 (1-2) s. 103-113 (2015)
• Lepiarczyk M, Kałuża Z, Bielawska A, Czarnomysy R, Gornowicz A, Bielawski K. Cytotoxic activity of octahydropyrazin [2,1-a:5,4-a'] diisoquinoline derivatives in human breast cancer cells. Archives of Pharmacal Research, s.1-14 (2014)
• Gornowicz A, Kałuża Z, Bielawska A, Gabryel- Porowska H, Czarnomysy R, Bielawski K. Cytotoxic efficacy of a novel dinuclear platinum(II) complex used with anti-MUC1 in human breast cancer cells. Molecular and Cellular Biochemistry s.1-10 (2014)
• Gabryel-Porowska H, Gornowicz A, Bielawska A, Wójcicka A, Maciorkowska E, Grabowska SZ, Bielawski K. Mucin levels in saliva of adolescents with dental caries. Medical Science Monitor, 20 s. 72-77 (2014)
• Gornowicz A, Tokajuk G, Bielawska A, Maciorkowska E, Jabłoński R, Wójcicka.: The assessment of sIgA, histatin-5 and lactoperoxidase levels in saliva of adolescents with dental caries. Medical Science Monitor, 20 s. 1095-1100 (2014)