Research activities:
1) Xenobiotics effect on signal transduction and apoptosis in human leukocytes.
2) The role of cytokines in the phenomenon neutrophils extracellular traps (NETs) in the states of physiology and pathology.
3) The effect of ginsenosides on the activity and survival of neutrophils in the course of infectious diseases.
4) The role of the signaling pathways for the synthesis and release of TNF family factors in malignancy.
Research tasks are implemented using the techniques of molecular biology, flow cytometry, fluorescence microscopy and enzyme-linked immunosorbent methods.
Publications:
- Marzena Garley, Dorota Dziemiańczyk-Pakieła, Kamil Grubczak, Arkadiusz Surażyński, Dorota Dąbrowska, Wioletta Ratajczak-Wrona, Jolanta Sawicka-Powierza, Jan Borys, Marcin Moniuszko, Jerzy Pałka, Ewa Jabłońska. Differences and similarities in the phenomenon of NETs formation in oral inflammation and in oral squamous cell carcinoma. Journal of Cancer 2018 : 9, s. 1958-1965
Marzena Garley, Ewa Jabłońska. Heterogeneity among neutrophils. Archivum Immunologiae et Therapiae Experimentalis 2018 : 66, 1, s. 21-30
Karolina Nowak, Wioletta Ratajczak-Wrona, Maria Górska, Ewa Jabłońska. Parabens and their effects on the endocrine system. Molecular and Cellular Endocrinology 2018 : 474, s. 238-251
Wioletta Ratajczak-Wrona, Karolina Nowak [S.D.], Marzena Garley, Marlena Tynecka, Ewa Jabłońska. Sex-specific differences in the regulation of inducible nitric oxide synthase by bisphenol A in neutrophils. Human & Experimental Toxicology 2018 : 29, 1, s.19 -23
Karolina Nowak [S.D.], Wioletta Ratajczak-Wrona, Marzena Garley, Ewa Jabłońska. The effect of ethanol and N-nitrosodimethylamine on the iNOS-dependent NO production in human neutrophils. Role of NF-KappaB. Xenobiotica 2018 : 48, 5, s. 498-505
Dorota Dąbrowska, Ewa Jabłońska, Marzena Garley, Jolanta Sawicka-Powierza, Karolina Nowak. The phenomenon of neutrophil extracellular traps in vascular diseases. Archivum Immunologiae et Therapiae Experimentalis 2018 : 66, 4, s. 273-281
Wioletta Ratajczak-Wrona, Ewa Jabłońska. The signaling pathways in nitric ocide production by neutrophils exposed to N-nitrosodimethylamine. Letters in Drug Design & Discovery 2018 : 15, 6 pp 1570-1808
Marzena Garley, Ewa Jabłońska, Arkadiusz Surażyński, Kamil Grubczak, Wioletta Ratajczak-Wrona, Agnieszka Iwaniuk, Dorota Dąbrowska, Jerzy Aleksander Pałka, Marcin Moniuszko. Cytokine network & NETs. Folia Biologica (Praha) 2017 : 63, 5-6, s. 182-189
Ewa Jabłońska, Bożena Słodczyk, Natalia Wawrusiewicz-Kurylonek, Dorota Dziemiańczyk-Pakieła, Marzena Garley, Wioletta Ratajczak-Wrona, Jan Borys, Adam Krętowski. Comparison of B-cell activating factor expression in neutrophils in patients with potentially malignant disorders and patients with cancer in the same site. Clinical Laboratory 2016 : 62, 8, s. 1507-1514
Marzena Garley, Ewa Jabłońska, Jolanta Sawicka-Powierza, Janusz Kłoczko, Jarosław Piszcz, Magdalena Kakareko, Wioletta Ratajczak-Wrona, Angelika Charkiewicz, Wioleta Omeljaniuk, Andrzej Szpak. Expression of IL-1 and IL-6 and their natural regulators in leukocytes of B-cell chronic lymphocytic leukaemia patients. Advances in Medical Sciences 2016 : 61, 2, s. 187-192
Marzena Garley, Ewa Jabłońska, Dorota Dąbrowska. NETs in cancer. Tumor Biology 2016 : 37, 11, s. 14355-14361
D[orota] Dąbrowska, Ewa Jabłońska, M[arzena] Garley, W[ioletta] Ratajczak-Wrona, A[gnieszka] Iwaniuk. New aspects of the biology of neutrophil extracellular traps. Scandinavian Journal of Immunology 2016 : 84, 6, s. 317-322
A[gnieszka] Iwaniuk, E[wa] Jabłońska, Jakub Jabłoński, W[ioletta] Ratajczak-Wrona, M[arzena] Garley. Expression of selected proteins of the extrinsic and intrinsic pathways of apoptosis in human leukocytes exposed to N-nitrosodimethylamine. Human & Experimental Toxicology 2015 : 34, 6, s. 591-600