Medical University of Bialystok. Research & Science.

Research activity:

evaluation of diffuse neuroendocrine cells (DNES) in human and experimental animals in various physiological and pathological conditions
evaluation of hormones, receptors for those hormones, biologically active proteins, WNT/β-catenin pathway, S100 calcium binding proteins and CacyBP/SIP in various cancers
evaluation of endocannabinoid system, WNT/β-catenin pathway, S100 calcium binding proteins and CacyBP/SIP in human and experimental animals in various physiological and pathological conditions.
evaluation of impact of presence of foreign bodies in the oral cavity (piercings, dental fillings, prosthetic fillings, dental appliances) on the morphology and function of mucosal epithelial cells.

statement the changes in the total number of studied neuroendocrine cells and differences in intensity of immunohistochemical reactions determining tested hormones and biological active proteins in various organs of uremic rats and hypertension rats
demonstrate, that the DNES cells play a important role in the modulation of functional disorders, as a consequence of end organ damage in the course of renal failure or hypertension
statement the changes in density of cannabinoid receptors and content of S100 calcium binding proteins and CacyBP/SIP in human heart with ageing
statement the changes in density of cannabinoid receptors and expression of those receptors in various organs of uremic and hypertensive rats
statement the changes in content and expression of S100 calcium binding proteins and CacyBP/SIP in in various organs of uremic and hypertensive rats
statement the changes in expression of hormones, receptors for those hormones and biologically active proteins, activity of WNT/β-catenin pathway, expression of S100 calcium binding proteins and CacyBP/SIP in various cancers
statement the changes in activity of WNT/β-catenin pathway in various organs of rats with spontaneous, renovascular and DOCA-salt hypertension
demonstrate, that presence of foreign bodies in the oral cavity significantly affect on the morphology, survivability and function of mucosal epithelial cells.