Medical University of Bialystok. Research & Science.

Scientific activity

studies on the mechanisms of action of toxic substances (heavy metals, nitrosoamines, pesticides, ethyl alcohol)
searching for new indicators of exposure to toxic substances
interactions of toxic substances with bioelements and ethyl alcohol
research on the possibility of using zinc in prevention from cadmium toxicity
ecotoxicological studies and estimation of herbal contamination with heavy metals
researches (according to the standard of Good Laboratory Practise) in the area of toxicological evaluation of chemical substances, potential medicines and medical devices

Techniques

atomic - absorption spectrometry (AAS)
gas chromatography with mass detection (GC-MS)
high-performance liquid chromatography (HPLC)
flow cytometry
immunoenzymatic methods
immunofluorescence in polarized light
UV-VIS spectrophotometry
microwave mineralization
solid phase extraction (SPE) and solid phase microextraction (SPME)

Publications

Brzóska M.M., Kozłowska M., Rogalska J.: The beneficial impact of zinc supplementation on the vascular tissue of the abdominal aorta under repeated intoxication with cadmium: a study in an in vivo experimental model. Nutrients 2022, 14, 4080. https://doi.org/10.3390/nu14194080
Ruczaj A., Brzóska M.M.: Environmental exposure of the general population to cadmium as a risk factor of the damage to the nervous system: A critical review of current data. J Appl Toxicol. 2022, 1–23. DOI: 10.1002/jat.4322, http://212.33.76.61/cgi-bin/expertus3.cgi

Onopiuk B.M., Dąbrowska Z.N., Rogalska J., Brzóska M.M., Dąbrowski A.,Bijowski K., Onopiuk P., Mroczko B., Orywal K., Dąbrowska E.: The beneficial impact of the black chokeberry extract against the oxidative stress in the sublingual salivary gland of rats intoxicated with cadmium. Oxidative Medicine and Cellular Longevity, 2021, Article ID 6622245, https://doi.org/10.1155/2021/6622245
Brzóska M.M., Kozłowska M., Rogalska J., Gałażyn-Sidorczuk M., Roszczenko A., Smereczański N.: Enhanced zinc intake protects against oxidative stress and its consequences in the brain: a study in an In vivo rat model of cadmium exposure. Nutrients 2021, 13, 26 pp, Article ID 478 doi: 10.3390/nu13020478.
Olszewska E., Rogalska J., Brzóska M.M.: The association of oxidative stress in the uvular mucosa with obstructive sleep apnea syndrome: A clinical study. J. Clin. Med. 2021, 10, 1132. https://doi.org/10.3390/jcm10051132.
Biernacki M., Brzóska M.M, Markowska A., Gałałażyn-Sidorczuk M., Cylwik B., Gęgotek A., Skrzydlewska E.: Oxidative stress and its consequences in the blood of rats irradiated with UV: protective effect of cannabidiol. Antioxidants 2021, 10, 821.
Kozłowska M., Brzóska M.M., Rogalska J., Galicka A.: The impact of a polyphenol-rich extract from the berries of Aronia melanocarpa L. on collagen metabolism in the liver: a study in an in vivo model of human environmental exposure to cadmium. Nutrients 2020, 12, 2766; doi:10.3390/nu12092766, 35pp.
Borowska S., Tomczyk M., Strawa J.W., Brzóska M.M.: Estimation of the chelating ability of an extract from Aronia melanocarpa L. berries and its main polyphenolic ingredients towards ions of zinc and copper. Molecules 2020, 25, 1507.
Dąbrowski A., Onopiuk B.M., Car H., Onopiuk P., Dąbrowska Z. N., Rogalska J., Brzóska M.M., Dąbrowska E. : Beneficial impact of an extract from the berries of Aronia melanocarpa L. on the oxidative-reductive status of the submandibular gland of rats exposed to cadmium. Antioxidants 2020, 9, 185.
Matwiejczuk N., Galicka A., Brzóska M.M.: Review of the safety of application of cosmetic products containing parabens. J. Appl. Toxicol., 2020, 40, 176-210.
Mężyńska M., Brzóska M.M., Rogalska J., Galicka A.: Extract from Aronia melanocarpa L. berries protects against cadmium-induced lipid peroxidation and oxidative damage to proteins and DNA in the liver: a study using a rat model of environmental human exposure to this xenobiotic. Nutrients 2019, 11, 758.
Mężyńska M., Brzóska M.M., Rogalska J., Piłat-Marcinkiewicz B.: Extract from Aronia melanocarpa L. berries prevents cadmium-induced oxidative stress in the liver: a study in a rat model of low-level and moderate lifetime human exposure to this toxic metal. Nutrients 2019, 11, 21.
Mężyńska M., Brzóska M.M.: Review of polyphenol-rich products as potential protective and therapeutic factors against cadmium hepatotoxicity. J. Appl. Toxicol., 2019, 39, 117-145.
Borowska S., Brzóska M.M., Tomczyk M.: Complexation of bioelements and toxic metals by polyphenolic compounds - implications for health. Curr. Drug Targets, 2018, 19, 14, 1612-1638.
Mężyńska M., Brzóska M.M.: Environmental exposure to cadmium-a risk for health of the general population in industrialized countries and preventive strategies. Environ. Sci. Pollut. Res. Inter., 2018, 25, 4, 3211-3232.
Brzóska M.M., Gałażyn-Sidorczuk M., Borowska S.: Metals in cosmetics. In: Metal Allergy: from dermatitis to implant and device failure, eds.: Chen J.K., Thyssen J.P., 2018, 15, 177-196, ISBN 978-3-319-58502-4, Cham, Switzerland, Springer International Publishing AG.
Andrulewicz-Botulińska E., Wiśniewska R., Brzóska M.M., Rogalska J., Galicka A.: Beneficial impact of zinc supplementation on the collagen in the bone tissue of cadmium-exposed rats. J. Appl. Toxicol., 2018, 38, 996-1007.
Kulikowska-Karpińska E., Zdanowicz M., Gałażyn-Sidorczuk M.: Ocena stężenia miedzi w moczu osób palących papierosy. Wiad. Lek., 2017, 70, 4, 697-702.
Brzóska M.M., Roszczenko A., Rogalska J., Gałażyn-Sidorczuk M., Mężyńska M.: Protective effect of Chokeberry (Aronia melanocarpa L.) extract against cadmium impact on the biomechanical properties of the femur: a study in a rat model of low and moderate lifetime women exposure to this heavy metal. Nutrients, 2017, 9, 543.
Borowska S., Brzóska M.M., Gałażyn-Sidorczuk M., Rogalska J.: Effect of an extract from Aronia melanocarpa L. berries on the body status of zinc and copper under chronic exposure to cadmium: an in vivo experimental study. Nutrients, 2017, 9, 1374.
Brzóska M.M., Rogalska J., Roszczenko A., Gałażyn-Sidorczuk M., Tomczyk M.: The mechanism of the osteoprotective action of a polyphenol-rich Aronia melanocarpa extract during chronic exposure to cadmium is mediated by the oxidative defense system. Planta Med., 2016, 82, 7, 621-631.
Brzóska M., Borowska S., Tomczyk M.: Antioxidants as a potential preventive and therapeutic strategy for cadmium. Curr. Drug Targets, 2016, 17, 12, 1350-1384.
Borowska S., Brzóska M.: Chokeberries (Aronia melanocarpa) and their products as a possible means for the prevention and treatment of noncommunicable diseases and unfavorable healt effects due to exposure to xenobiotics. Comp. Rev. Food Sci. Food Saf., 2016, 15, 6, 982-1017.
Brzóska M.M., Rogalska J., Gałażyn-Sidorczuk M., Jurczuk M., Roszczenko A., Tomczyk M.: Protective effect of Aronia melanocarpa polyphenols against cadmium-induced disorders in bone metabolism: A study in a rat model of lifetime human exposure to this heavy metal. Chem. Biol. Interact., 2015, 229, 132-146.
Kulikowska-Karpińska E., Czerw K.: Ocena stężenia 8-hydroksy-2-deoksyguanozyny (8-OHdG) w moczu osób palących papierosy. Wiad. Lek., 2015, 68, 1, 32-38.
Borowska S., Brzóska M.M.: Metals in cosmetics: implications for human health. J. Appl. Toxicol., 2015, 35, 6, 551-572.
Brzóska M.M., Gałażyn-Sidorczuk M., Jurczuk M., Tomczyk M.: Protective effect of Aronia melanocarpa polyphenols on cadmium accumulation in the body: a study in a rat model of human exposure to this metal. Curr. Drug Targets, 2015, 16, 13, 1470-1487.