Research activity:

• Na+/H+ exchanger and its role in platelet activation
• The mechanism of platelet procoagulant response
• Clot retraction and fibrinolysis
• Platelet energy metabolism
• The interactions of drugs(medications) with blood platelets
• Hemostatic balance in patients with Polycythemia Vera, Asthma, Diabetes, Cancer ...
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Selected publications:

• Rusak T, Ciborowski M, Uchimiak-Owieczko A, Piszcz J, Radziwon P, Tomasiak M. Evaluation of hemostatic balance in blood from patients with polycythemia vera by means of thromboelastography: The effect of isovolemic erythrocytapheresis. Platelets. 2012; 23: 455-462.
• Misztal T, Przesław K, Rusak T, Tomasiak M. Peroxynitrite - altered platelet mitochondria-A new link between inflammation and hemostasis. Thrombosis Research 2013; 13: e17-25
• Rusak T, Piszcz J, Misztal T, Brańska-Januszewska J, Tomasiak M. Platelet-related fibrinolysis resistance in patients suffering from PV. Impact of clot retraction and isovolemic erythrocytapheresis. Thrombosis Research 2014; 134: 192-198.
• Misztal T, Rusak T, Tomasiak M. Clinically relevant HOCl concentrations reduce clot retraction rate via the inhibition of energy production in platelet mitochondria. Free Radical Research 2014; 48: 1443-53.
• Rusak T, Misztal T, Piszcz J, Tomasiak M. Nitric oxide scavenging by cell-free hemoglobin may be a primary factor determining hypertension in polycythemic patients. Free Radical Research 2014; 48: 230-238.
• Misztal T, Rusak T, Brańska-Januszewska J, Ostrowska H, Tomasiak M. Peroxynitrite may affect fibrinolysis via the reduction of platelet-related fibrinolysis resistance and alteration of clot structure. Free Radical Biology & Medicine. 2015; 89: 533-547. 
• Tomasiak-Łozowska MM, Misztal R, Rusak T, Brańska-Januszewska J, Bodzenta-Łukaszyk A, Tomasiak M. Asthma is associated with reduced fibrinolytic activity, abnormal clot architecture, and decreased clot retraction rate. Allergy  2017; 72:314-319.
• Rusak T, Misztal T, Rusak M, Branska-Januszewska J, Tomasiak M. Involvement of hyperglycemia in the development of platelet procoagulant response: the role of aldose reductase and platelet swelling. Blood Coagulaton & Fibrinolysis, 2017, 28:443-451.
• Misztal T, Golaszewska A, Tomasiak-Lozowska MM, Iwanicka M, Marcinczyk N, Leszczynska A, Chabielska E, Rusak T. The myeloperoxidase product, hypochlorous acid, reduces thrombus formation under flow and attenuates clot retraction and fibrinolysis in human blood. Free Radical Biology  & Medicine 2019; 41: 426-437.
• Gołaszewska A, Misztal T, Marcińczyk N, Chabielska E, Rusak T. Adrenaline may contribute to prothrombotic condition via augmentation of platelet procoagulant response, enhancement of fibrin formation, and attenuation of fibrinolysis.  Frontiers in Physiology  2021, 12: 65788
• Misztal T, Gołaszewska A, Marcińczyk N, Tomasiak-Łozowska M, Szymanowska M, Chabielska E, Rusak T. Natural polyphenols may normalize hypochlorous acid-evoked hemostatic abnormalities in human blood. Antioxidants  2022; 11(4):779