Name of course/module

Pharmacology

Name of unit(s) in which the course is implemented

Department of Pharmacology

E-mail of the unit

zfarm@umb.edu.pl

Faculty

Faculty of Medicine with the Division of Dentistry and Division of Medical Education in English

Major

Medicine

Mode of study

Long-cycle studies

Form of study

full-time x                                  part-time x

Language of the course

Polish                                                   English x

Course type

obligatory x                                 facultative £

Year/ semester

I £   II £   III x   IV £   V £  VI £

1 £   2 £   3 £   4 £   5 x   6 x   7 £   8 £   10 £

11 £   12 £

Introductory courses and essential requirements

The student has obligatorily passed physiology and biochemistry, obligatorily microbiology and pathophysiology and has the range of knowledge, skills and competences after the above mentioned subjects of basic sciences according to the study programme of the first and second year.

Number of hours of teaching divided into forms of teaching

120 didactic hours: lectures 40 hours, practical classes 70 hours and 10 hours of seminars

Course assumptions and objectives

The basic aim of teaching Pharmacology and toxicology of drugs is to answer the question how and why drug acts in humans. Familiarizing the student with pharmacological actions of particular drug groups and resulting contraindications to their use. Familiarizing the student acquainted undesirable and toxic effects of drugs and their interactions. Preparing the student to acquire the practical skill of writing prescriptions with basic indications of pharmacotherapy.

Teaching methods

- transfer of knowledge in a lecture form

-  practical classes (exercises) especially in the practical skill of writing prescriptions

- discussion

- presentation

- independent searching for knowledge

- literature analysis

- consultations (according to individual needs with teachers of the Department and online)

Name and surname of the tutor

prof. dr hab. Adam Hołownia – Head of the course

Scientific & didactic and didactic staff employed at the Department of Pharmacology

Name and surname of the person responsible for teaching

prof. dr hab. Adam Hołownia

Dr n. med. Edyta Gołąbiewska

Symbol

and number of learning

in accordance with the educational standard and other subject learning outcomes

Description of major-related learning outcomes

Type of training

Method of verification of assumed learning outcomes

Knowledge

C.W35

Knows and understands individual groups of medicinal products

Lectures, practical classes

Formative methods, e.g.:

 - written examination (MCQ - test)

Formative methods, e.g.

- observation of student work

- assessment of activity during classes

- assessment of individual actions (prescriptions, tests)

- evaluation of preparation for classes

- discussion during classes

- partial assessment (prescriptions, tests)

C.W36

Knows the main mechanisms of drug action and their age-dependent transformations in the body

C.W37

Knows and understands the influence of disease processes on drug metabolism and elimination

C.W38

Knows the basic principles of pharmacotherapy

C.W39

He/she knows the most important adverse effects of medicines, including those resulting from their interactions

C.W40

Understands the problem of drug resistance, including multidrug resistance

C.W41

Knows the indications for genetic testing in order to individualise pharmacotherapy

C.W42

Knows the basic directions of therapy development, in particular the possibilities of cell, gene and targeted therapy in specific diseases

C.W43

He knows basic concepts of general toxicology

C.W44

Knows groups of drugs which abuse can lead to poisoning

C.W45

He/she knows the symptoms of the most common acute poisonings, including alcohol, drugs, psychoactive substances, heavy metals and selected groups of drugs

Skills

C.U13

Performs simple pharmacokinetic calculations

Practical classes

Summarising methods, e.g.:

 - completion of a specific task, ability to write a prescription

Formative methods, e.g.

- observation of student work

- assessment of activity during classes

- assessment of individual actions (prescriptions, tests)

- evaluation of preparation for classes

- discussion during classes

- partial assessment (prescriptions, tests)

C.U14

Selects drugs in appropriate doses to correct pathological phenomena in the body and in individual organs

C.U15

Designs a scheme of rational, empirical and targeted chemotherapy of infections

C.U16

Can correctly prepare records of all prescription forms of medicinal substances

C.U17

Uses pharmaceutical reference books and databases of medicinal products

C.U18

Can assess toxicological risk in specific age groups and in states of liver and kidney failure, and prevent drug poisoning

social competences

K1

respects medical confidentiality and patient rights

Practical classes

Summarising methods, e.g.:

continuous assessment by the teacher at each practical class

Formative methods, e.g.

- observation of student work

- discussion during classes

K3

is guided by the welfare of the patient

K4

perceives and recognises own limitations and makes self-assessments of deficits and learning needs

K6

promotes pro-health behaviour

K7

uses objective sources of information

K10

formulates opinions on various aspects of professional activity

K11

accepts responsibility connected with decisions made within the scope of professional activity, including in terms of his/her own and other people's safety

ECTS credits

10

Student workload

Form of activity

Number of hours to complete the activity

Activities requiring participation of the tutor:

1. Course completion: lectures (according to the study plan)

40

2. Course completion: practical classes (according to the study plan)

70

3. Course completion: seminars (according to the study plan))

10

4. Course completion: optional classes

–

5. Participation in consultations

15

hours total: 135

Independent student work:

1. Self-preparation for theoretical and practical classes (making a project, documentation, case description, etc.)

35

2. Self-preparation for assessments/colloquiums

35

3. Self-preparation for the final examination/assessment

20

hours total: 90

Learning content of the course

Learning Outcomes

(symbol and number)

Subject

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c w34,35,36,37,38,39,40,41,42,43,44,

c u 13,14,15,16,17,18

c w34,35,36,37,38,39,40,41,42,43,44,

c u 13,14,15,16,17,18

c w34,35,36,37,38,39,40,41,42,43,44,

c u 13,14,15,16,17,18

c w34,35,36,37,38,39,40,41,42,43,44,

c u 13,14,15,16,17,18

c w34,35,36,37,38,39,40,41,42,43,44,

c u 13,14,15,16,17,18

Lectures

Introduction to Pharmacology. Pharmacodynamics.

Pharmacokinetics.

Autacoids.

Hormones of adrenal glands.

Hormones of reproductive system and calcium regulating hormones.

Antispastic agents.

Sympathetic nervous system pharmacology.

Coanalgetics.

Antiepileptic drugs.

Psychomimetic agents. Drugs of abuse.

Antiplatelet, anti-coagulant agents.

Diuretics.

Treatment of dyslipidemias.

Antiarrhythmics

Drugs used in gastro-intestinal diseases.

Fundamentals of Antibiotic Therapy.

Antibiotics and chemotherapeutics.

Antifungal drugs. Antiparasitic agents.

Immunotherapy.

Drug toxicology. 

Practical classes

Module I - Basic general pharmacology and pharmacokinetics, pharmacodynamics. Endocrine Pharmacology.

Class 1.

General pharmacology with elements of pharmacodynamics. Fundamentals of pharmacology.

Class 2.

Pharmacokinetics.

Class 3.

Pharmacology of endocrine systems part. I: Hormones of the hypothalamus and pituitary. Hormones of the adrenal cortex.

Class 4.

Pharmacology of endocrine systems part. II: Thyroid hormones and drugs used in thyroid diseases. Pancreatic hormones and drugs used in the treatment of diabetes.

Class 5.

Calcium regulating hormones. Hormones of the reproductive system.

Quiz 1.

Module II- Autonomic and central nervous system drugs. Analgesics.

Class 6.

Drugs of the cholinergic system. Relaxants, ganglioplegics.

Class 7.

Drugs of the adrenergic system.

Class 8.

Analgesic drugs: non-steroidal anti-inflammatory drugs and opioid drugs. Coanalgesics

Class 9.

CNS drugs (part 1): Pharmacology of local and general anaesthetic drugs. Sedative and hypnotic drugs.

Class 10.

Drugs used in neurodegenerative disorders (Alzheimer, Parkinson’s disease). Antiseizure agents.

Class 11.

Antidepressants agents. Antipsychotic drugs and lithium.Drugs of abuse.

Quiz 2.

Module III -  Drugs affecting the cardiovascular system, renal function, haematopoietic system and coagulation system. Drugs of the respiratory system. Drugs of the digestive system.

Class 12.

Agents used in anemias, Hematopoietic growth factors, Drugs used in disorders of coagulation.

Class 13.

Antihypertensive agents.

Class 14.

Drugs used in the treatment of angina pectoris.

Class 15.

Drugs used in the heart failure.

Class 16.

Drugs used in the treatment of asthma, chronic obstructive pulmonary

disease and allergies

Class 17.

Drugs used in the treatment of gastrointestinal disorders.

Quiz 3.

Module IV – Chemotherapy. Immunology            .

Class 18.

Antimicrobials  part 1. Principles of antimicrobial use: beta-lactam antibiotics and other cell wall and membrane active antibiotics

Class 19.

Antimicrobials part 2: Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, Aminoglycosides and Spectinomycin; Chemotherapeutics (Sulfonamides, Trimethoprim, Fluoroquinolones); Miscellaneous antimicrobial drugs

Class 20.

Antiviral agents, antifungal agents, antihelminthic agents

Class 21

Anticancer agents. Immunotherapy. Drugs used in rheumatoid arthritis and gout.

Class 22.           

Drug toxicology. Drug interactions.

Quiz 4.

Obligatory literature: (1-2 items)

Supplementary literature: (1-2 items)

Criteria for the assessment of the achieved learning outcomes and the form and conditions of obtaining credit for the course:

1. Compulsory classes (lectures, exercises, seminars, quizzes) are conducted according to the timetable posted on the plan notice board and on the website: www.umb.edu.pl/wl/zaklad-farmakologii

2. Practical classes are held in the classrooms of the Department of Pharmacology.

3. Programme of practical classes is divided into 4 modules, each module ends with a quiz (test).

4. Students who have passed all exercises in the module are allowed to take the quiz. 60% of correct answers are required to pass the test. A failed quiz is corrected only once.

5.Absences from classes and lectures should be excused at the latest during the next classes and a copy of the document (medical exemption, dean's leave, etc.) should be submitted at the Department.

6. Students who did not pass the practical classes due to excused absence should make up the classes with another group or, if it is not possible, pass the practical classes with the supervising assistant within 2 weeks (test according to the material required during class). A failed exercise is corrected once.

7. Unjustified absences cannot be made up.

8. Written assignments, after they have been checked and evaluated, are made available to students.

9. The condition of allowing to take the final examination is

      - Passing the practical classes, attendance at obligatory classes and seminars

      - Passing all the 4 quizzes

10.  The final exam in the form of a one-choice test will be held in the summer session after the VI semester.

11. A prerequisite for passing the final examination is obtaining at least 60% of correct answers

    The following grading scale applies to the quizzes and the final examination:

        < 60% - failing grade  (2) (positive answers or points)

           60-69% satisfactory grade (3)

           70-79% satisfactory plus grade (3.5)

           80-89% good grade (4)

           90-95% good plus grade (4,5)

          >96% very good (5)

12. The results of the quizzes and the final examination will be posted on the notice board and will also be published on the establishment's website.